The proton-coupled amino acid transporter, PAT1, is known to be responsible for intestinal absorption drug substances such as gaboxadol and vigabatrin. aim of the present study was investigate, if 17-α-ethinyl-estradiol (E-E2) 17-β-estradiol (E) inhibit PAT1-mediated proline taurine in vitro Caco-2 cells vivo using Sprague-Dawley rats assess potential taurine-drug interactions. E E-E2 inhibited...

the adsorption properties and mechanics of selected endocrine disrupting compounds; 17 β-estradiol, 17 α – ethinylestradiol and bisphenol a on locally available black tea leaves waste and granular activated carbon were investigated. the results obtained indicated that the kinetics of adsorption were ph, adsorbent dose, contact time and temperature dependent with equilibrium being reached at 20 ...

the correlation between serum steroid hormones, testosterone (t), 17β-estradiol (e2), and progesterone (p) and weight of female fishes, biological characteristics of gonad (e.g. fertilization rate, fluid egg rate, gonadosomatic index , polarization index and oocyte diameter) in 10 female of the migratory population of sterlet (acipenser ruthenus) and 5 female of the migratory population of sibe...

In this investigation, serum steroid hormones such as testosterone (T), 17β-estradiol (E2) and progesterone (P) in 12 female of the migratory population of Common carp (Cyprinus carpio) in southeast of Caspian Sea during a year from May 2011 to May 2012 were studied. The results of present study revealed that changes in levels of steroid hormones, (E2) and (T) were closely correlated to ovarian...

Nonylphenol (NP) is an endocrine disrupting chemical which has been shown to be able to modulate endocrine system of various organisms by different mechanisms. The objective of this study was to investigate the potential effects of  4-NP and 17-β-estradiol (E2) on immune parameters (IgM level and lysozyme activity) of   Koi carp (Cyprinus the carpio carpio)  in an attempt to expand the knowledg...

The current study was undertaken to determine the 17-β Estradiol (E2) and Progesterone (P4) levels in different milk products some baby follow-on samples collected from retail markets Türkiye. For this purpose, a total of 50 8 product groups with fat levels, production technologies, series were analyzed for natural P4 E2 using commercial ELISA kit. highest level determined UHT whole (3%) (39.20...

Among Chinese soft-shelled turtles, Pelodiscus sinensis, males have a richer nutritional value and higher market price than females. All-male offspring were obtained by 17β-estradiol (E2). However, the molecular mechanisms of E2 inducing sexual reversal remain unclear. In this study, we cloned estrogen nuclear receptors (ERs) from P. sinensis investigated their expression profiles. We examined ...

Background & Aims: Adult neurogenesis occurs in the two main areas of the brain of most mammalian species in; sub ventricular zone, and the dentate gyrus of the hippocampus. Many factors such as 17-β estradiol affect neurogenesis in the hippocampus. The aim of this study was to investigate the effect of exogenous 17-β estradiol on neurogenesis in the ovariectomized (OVX) mice. Materials & Meth...

Stroke is a leading cause of permanent disability and death. It is well accepted that the principal mammalian estrogen (E2), 17-β estradiol, provides robust neuroprotection in a variety of brain injury models in animals of both sexes. E2 enhances neurogenesis after stroke in the subventricular zone; however, it is unknown if these cells survive long-term or enhance functional recovery. In this ...